Comment 1 for bug 385237

Hi. Could you run "apport-collect -p ubuntuone-client 385237" please? I'm not sure why you wouldn't be able to connect, or see the nautilus extension working (though if you installed and didn't restart nautilus, it would not be getting loaded there). The apport-collect command will attach logs so that we can more easily determine what is gong on. I've been running the client on Karmic without any issues.