E: dpkg was interrupted, you must manually run 'sudo dpkg --configure -a' to correct the problem. E: _cache->open() failed, please report.

That doesn't look like a Nautilus bug

Thank you for taking the time to report this issue and helping to make Ubuntu better. Examining the information you have given us, this does not appear to be a bug report so we are closing it and converting it to a question in the support tracker. We appreciate the difficulties you are facing, but it would make more sense to raise problems you are having in the support tracker at https://answers.launchpad.net/ubuntu if you are uncertain if they are bugs. For help on reporting bugs, see https://help.ubuntu.com/community/ReportingBugs#When%20not%20to%20file%20a%20bug.

Please try the following:

1) Open a terminal (Applications->Accessories->Terminal).
2) Type the following command and then press <Enter>:

sudo dpkg --configure -a

3) You will be prompted for your password. Type your password and then press <Enter>. Your password will not display on screen when you type, so type carefully.

4) When the command completes a new prompt will appear. Close the terminal and try to do whatever task gave you the error message.

Can you paste what messages it gives you when you type:

$ sudo dpkg --configure -a

Thank you Steven, I am a linux novice and that worked as stated.
Thank you Chris Coulson, again I'm a linux novice and wasn't sure where this should go. I appreciate the clarification.
Nandan Vaidya, Sorry, the script ran for somewhere between 10 and 30 lines, but it took care of the problem.

Thanks Steven Danna (ssd7) for the help, I followed your instruction, and got the answer right from the terminal , my mint persistent on a usb run out of space, thank you again.