can hover take place within a region?

I have a "hover(Pattern("14412969663.png").similar(0.44).targetOffset(-7,14))" going off but the screenshot it's looking for can change slightly over a perioud of time.
lowering the match to far leads to false positives.
I solved the problem with this.
wait(Pattern("14412969663.png").similar(0.30).targetOffset(-135,4), 1800)
click(Pattern("14412969663.png").similar(0.30).targetOffset(-135,4))

But this is taking longer then I care for, the image it's looking for only appears in about a 5th of the screen, so if I could have it all going of in a region I could reduce the wait time down to 2 mins maybe.

I get my knuckles wrapped on here if I don't prove I tried to work it out, so I had a look on http://doc.sikuli.org/region.html
Region.find(). looked like what I'm after, but it didn't explain how you define the region then incorporate Region.find().
It's really not friendly to people who are still learning to code.